Review




Structured Review

Santa Cruz Biotechnology md2
Md2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 42 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/MD-2+Antibody/pm40156005-50-19-37
Average 93 stars, based on 42 article reviews
md2 - by Bioz Stars, 2026-09
93/100 stars

Images

Related Articles

other:

Article Title: An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses
Article Snippet: Human anti-NF-κB p105/p50, Human anti-NF-κB p65, Anti-rabbit IgG HRP, Alexa flour 488 Secondary IgG, and proliferating cell nuclear antigen (PCNA) antibodies were purchased from Cell Signaling Technology (CST), whereas anti-MD2 and anti-TLR4 antibody were procured from Santa Cruz Biotechnology.

Article Title: An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses
Article Snippet: Antibodies Human anti-NF-κB p105/p50, Human anti-NF-κB p65, Anti-rabbit IgG HRP, Alexa flour 488 Secondary IgG, and proliferating cell nuclear antigen (PCNA) antibodies were purchased from Cell Signaling Technology (CST), whereas anti-MD2 and anti-TLR4 antibody were procured from Santa Cruz Biotechnology.

Article Title: An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses.
Article Snippet: MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).. Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host.. However, not much is known about the segments in MD2 that are responsible for LPS interaction or internalization of pathogen inside the defense cells.

Control:

Article Title: Der p2 Internalization by Epithelium Synergistically Augments Toll-like Receptor-Mediated Proinflammatory Signaling
Article Snippet: Neutralizing antibodies against human TLR2 and TLR4 were purchased from eBioscience (San Diego, CA, USA). .. Anti-MD2, anti-TLR2, anti-TLR4, and isotype control IgG antibodies were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). .. The signaling inhibitors SP600125 (JNK inhibitor), SB203580 (p38 inhibitor), PD98059 (ERK inhibitor), and BAY 11-7082 (IκB inhibitor) were purchased from Calbiochem (Merck, Germany).

Staining:

Article Title: Proinflammatory signal transduction pathway induced by Shigella flexneri porins in caco-2 cells
Article Snippet: .. TLR4/MD-2 complex was detected with anti-MD2 (IMG 415 Santa Cruz) and stained using the ECL system (Amersham Pharmacia Biotech, Piscataway, NJ). ..



Similar Products

86
Servicebio Inc anti md2
Anti Md2, supplied by Servicebio Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/80+anti+f4/pmc12893965-112-8-33
Average 86 stars, based on 1 article reviews
anti md2 - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier

93
Proteintech antibodies for md2
Antibodies For Md2, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/LY96%2FMD2+Antibody/pm41177411-54-0-23
Average 93 stars, based on 1 article reviews
antibodies for md2 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

93
Proteintech mouse monoclonal anti tau md2 1
Mouse Monoclonal Anti Tau Md2 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/LY96%2FMD2+Antibody/bio_rxiv__2025__10__02__680111-254-21-39
Average 93 stars, based on 1 article reviews
mouse monoclonal anti tau md2 1 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

93
Proteintech ly96
Ly96, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/LY96%2FMD2+Antibody/pm40830197-79-21-22
Average 93 stars, based on 1 article reviews
ly96 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

93
Proteintech antibodies targeting ly96 md2
Antibodies Targeting Ly96 Md2, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/LY96%2FMD2+Antibody/10__21203_slash_rs__3__rs___7085332_slash_v1-292-0-28
Average 93 stars, based on 1 article reviews
antibodies targeting ly96 md2 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

93
Santa Cruz Biotechnology md2
Md2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/MD-2+Antibody/pm40156005-50-19-37
Average 93 stars, based on 1 article reviews
md2 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

93
Proteintech mouse anti md2
Mouse Anti Md2, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/LY96%2FMD2+Antibody/pmc11988799-220-15-19
Average 93 stars, based on 1 article reviews
mouse anti md2 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

90
GeneTex biotinylated rabbit anti-md2 antibody gtx85517
<t>Clec7a–MD2</t> signaling mediates synaptic loss in PS19 mice. ( A – C ) Representative immunoblots of MD2 in ventral hippocampal lysate from WT or PS19 mice at 3 months ( A ), 6 months ( B ), and 9 months ( C ). ( D ) Representative immunoblots of hippocampus samples from AD patients. ( E ) Endogenous Clec7a was co-immunoprecipitated with MD2. ( F ) Quantitation of MD2 levels shown in panel ( A – C ) ( n = 6 mice per group, unpaired Student’s t test). ( G ) Quantitation of MD2 amounts in ( D ) ( n = 3 biologically independent samples per group, unpaired Student’s t test). ( H ) High resolution confocal images and 3D reconstructions show the presence of MD2 (magenta) tagged PSD95 (red) within Iba1 + cells (green) in the DG regions of hippocampal tissue from Laminarin-administered PS19 mice. White arrows indicating PSD95+ MD2+ puncta in Iba1 + cell. Scale bars, 5 μm. ( I ) Quantitation of MD2-PSD95 colocalized puncta ( n = 6 mice per group, one-way ANOVA test). ( J ) Quantitation of MD2-PSD95 colocalized puncta in Iba1 + cell ( n = 6 mice per group, one-way ANOVA test). * p < 0.05; ** p < 0.01; *** p < 0.001. Data are presented as mean ± SD.
Biotinylated Rabbit Anti Md2 Antibody Gtx85517, supplied by GeneTex, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+md2/anti+md2+gtx85517/pmc11988799-216-8-13
Average 90 stars, based on 1 article reviews
biotinylated rabbit anti-md2 antibody gtx85517 - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


Clec7a–MD2 signaling mediates synaptic loss in PS19 mice. ( A – C ) Representative immunoblots of MD2 in ventral hippocampal lysate from WT or PS19 mice at 3 months ( A ), 6 months ( B ), and 9 months ( C ). ( D ) Representative immunoblots of hippocampus samples from AD patients. ( E ) Endogenous Clec7a was co-immunoprecipitated with MD2. ( F ) Quantitation of MD2 levels shown in panel ( A – C ) ( n = 6 mice per group, unpaired Student’s t test). ( G ) Quantitation of MD2 amounts in ( D ) ( n = 3 biologically independent samples per group, unpaired Student’s t test). ( H ) High resolution confocal images and 3D reconstructions show the presence of MD2 (magenta) tagged PSD95 (red) within Iba1 + cells (green) in the DG regions of hippocampal tissue from Laminarin-administered PS19 mice. White arrows indicating PSD95+ MD2+ puncta in Iba1 + cell. Scale bars, 5 μm. ( I ) Quantitation of MD2-PSD95 colocalized puncta ( n = 6 mice per group, one-way ANOVA test). ( J ) Quantitation of MD2-PSD95 colocalized puncta in Iba1 + cell ( n = 6 mice per group, one-way ANOVA test). * p < 0.05; ** p < 0.01; *** p < 0.001. Data are presented as mean ± SD.

Journal: International Journal of Molecular Sciences

Article Title: Clec7a Signaling in Microglia Promotes Synapse Loss Associated with Tauopathy

doi: 10.3390/ijms26072888

Figure Lengend Snippet: Clec7a–MD2 signaling mediates synaptic loss in PS19 mice. ( A – C ) Representative immunoblots of MD2 in ventral hippocampal lysate from WT or PS19 mice at 3 months ( A ), 6 months ( B ), and 9 months ( C ). ( D ) Representative immunoblots of hippocampus samples from AD patients. ( E ) Endogenous Clec7a was co-immunoprecipitated with MD2. ( F ) Quantitation of MD2 levels shown in panel ( A – C ) ( n = 6 mice per group, unpaired Student’s t test). ( G ) Quantitation of MD2 amounts in ( D ) ( n = 3 biologically independent samples per group, unpaired Student’s t test). ( H ) High resolution confocal images and 3D reconstructions show the presence of MD2 (magenta) tagged PSD95 (red) within Iba1 + cells (green) in the DG regions of hippocampal tissue from Laminarin-administered PS19 mice. White arrows indicating PSD95+ MD2+ puncta in Iba1 + cell. Scale bars, 5 μm. ( I ) Quantitation of MD2-PSD95 colocalized puncta ( n = 6 mice per group, one-way ANOVA test). ( J ) Quantitation of MD2-PSD95 colocalized puncta in Iba1 + cell ( n = 6 mice per group, one-way ANOVA test). * p < 0.05; ** p < 0.01; *** p < 0.001. Data are presented as mean ± SD.

Article Snippet: For the immunoprecipitation of MD2, 1.5 μg of biotinylated rabbit anti-MD2 antibody (GTX85517, GeneTex) was incubated with 400–500 μg of protein sample overnight at 4 °C.

Techniques: Western Blot, Immunoprecipitation, Quantitation Assay